Anthrax Edema Factor Toxicity Is Strongly Mediated by the N-end Rule

Anthrax edema factor (EF) is a calmodulin-dependent adenylate cyclase that converts adenosine triphosphate (ATP) into 3’–5’-cyclic adenosine monophosphate (cAMP), contributing to the establishment of Bacillus anthracis infections and the resulting pathophysiology. We show that EF adenylate cyclase t...

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Detalles Bibliográficos
Autores principales: Leysath, Clinton E., Phillips, Damilola D., Crown, Devorah, Fattah, Rasem J., Moayeri, Mahtab, Leppla, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755998/
https://www.ncbi.nlm.nih.gov/pubmed/24015319
http://dx.doi.org/10.1371/journal.pone.0074474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755998/
https://www.ncbi.nlm.nih.gov/pubmed/24015319
http://dx.doi.org/10.1371/journal.pone.0074474

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