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The Interaction of Endothelin-1 and TGF-β1 Mediates Vascular Cell Remodeling

BACKGROUND: Pulmonary arterial hypertension is characterized by increased thickness of pulmonary vessel walls due to both increased proliferation of pulmonary arterial smooth muscle cell (PASMC) and deposition of extracellular matrix. In patients suffering from pulmonary arterial hypertension, endot...

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Detalles Bibliográficos
Autores principales: Lambers, Christopher, Roth, Michael, Zhong, Jun, Campregher, Christoph, Binder, Petra, Burian, Bernhard, Petkov, Ventzislav, Block, Lutz-Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756002/
https://www.ncbi.nlm.nih.gov/pubmed/24015303
http://dx.doi.org/10.1371/journal.pone.0073399