Cargando…

Protein Kinase C Zeta Regulates Human Pancreatic Cancer Cell Transformed Growth and Invasion through a STAT3-Dependent Mechanism

Pancreatic cancer is a very aggressive disease with few therapeutic options. In this study, we investigate the role of protein kinase C zeta (PKCζ) in pancreatic cancer cells. PKCζ has been shown to act as either a tumor suppressor or tumor promoter depending upon the cellular context. We find that...

Descripción completa

Detalles Bibliográficos
Autores principales: Butler, Amanda M., Scotti Buzhardt, Michele L., Li, Shuhua, Smith, Kristin E., Fields, Alan P., Murray, Nicole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756013/
https://www.ncbi.nlm.nih.gov/pubmed/24015205
http://dx.doi.org/10.1371/journal.pone.0072061