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Both PKA and Epac Pathways Mediate N-Acetylcysteine-Induced Connexin43 Preservation in Rats with Myocardial Infarction

Cardiac remodeling was shown to be associated with reduced gap junction expression after myocardial infarction. A reduction in gap junctional proteins between myocytes may trigger ventricular arrhythmia. Therefore, we investigated whether N-acetylcysteine exerted antiarrhythmic effect by preserving...

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Detalles Bibliográficos
Autores principales: Lee, Tsung-Ming, Lin, Shinn-Zong, Chang, Nen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756050/
https://www.ncbi.nlm.nih.gov/pubmed/24015194
http://dx.doi.org/10.1371/journal.pone.0071878