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In Vitro Formation of β Cell Pseudoislets Using Islet-Derived Endothelial Cells

β cell pseudoislets (PIs) are used for the in vitro study of β-cells in a three-dimensional (3-D) configuration. Current methods of PI induction require unique culture conditions and extensive mechanical manipulations. Here we report a novel co-culture system consisting of high passage β-cells and i...

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Detalles Bibliográficos
Autores principales: Spelios, Michael G., Kenna, Lauren A., Wall, Bonnie, Akirav, Eitan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756083/
https://www.ncbi.nlm.nih.gov/pubmed/24015227
http://dx.doi.org/10.1371/journal.pone.0072260