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In Vitro Formation of β Cell Pseudoislets Using Islet-Derived Endothelial Cells
β cell pseudoislets (PIs) are used for the in vitro study of β-cells in a three-dimensional (3-D) configuration. Current methods of PI induction require unique culture conditions and extensive mechanical manipulations. Here we report a novel co-culture system consisting of high passage β-cells and i...
Autores principales: | Spelios, Michael G., Kenna, Lauren A., Wall, Bonnie, Akirav, Eitan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756083/ https://www.ncbi.nlm.nih.gov/pubmed/24015227 http://dx.doi.org/10.1371/journal.pone.0072260 |
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