Suppression of Heme Oxygenase-1 by Prostaglandin E(2)-Protein Kinase A-A-Kinase Anchoring Protein Signaling Is Central for Augmented Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

PURPOSE: Prostaglandin (PG) E(2) is an immunomodulatory lipid mediator generated mainly via the cyclooxygenase-2 (COX-2) pathway from arachidonic acid at sites of infection and inflammation. A positive feedback loop of PGE(2) on COX-2 expression is critical for homeostasis during toll-like receptor...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Hyoung, Jung, Nam-Hee, Lee, Byoung-Hoon, Kim, Sang-Hoon, Jun, Jin Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756181/
https://www.ncbi.nlm.nih.gov/pubmed/24003391
http://dx.doi.org/10.4168/aair.2013.5.5.329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756181/
https://www.ncbi.nlm.nih.gov/pubmed/24003391
http://dx.doi.org/10.4168/aair.2013.5.5.329

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