Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses

Antagonism of N-methyl-D-aspartate (NMDA) receptors by phencyclidine (PCP) is thought to underlie its ability to induce a schizophrenia-like syndrome in humans, yet evidence indicates it has a broader pharmacological profile. Our previous lesion studies highlighted a role for serotonergic projection...

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Detalles Bibliográficos
Autores principales: Adams, Wendy K., Halberstadt, Adam L., van den Buuse, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756227/
https://www.ncbi.nlm.nih.gov/pubmed/24009584
http://dx.doi.org/10.3389/fphar.2013.00109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756227/
https://www.ncbi.nlm.nih.gov/pubmed/24009584
http://dx.doi.org/10.3389/fphar.2013.00109

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