A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk

Stress increases drug craving and relapse risk. The kappa opioid receptor gene (OPRK1) mediates stress responses. Here, we examined whether the OPRK1 rs6989250 C>G affects stress-induced cocaine craving and cortisol responses, subsequent cocaine relapse risk and the neural response to stress usin...

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Detalles Bibliográficos
Autores principales: Xu, K, Seo, D, Hodgkinson, C, Hu, Y, Goldman, D, Sinha, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756290/
https://www.ncbi.nlm.nih.gov/pubmed/23962922
http://dx.doi.org/10.1038/tp.2013.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756290/
https://www.ncbi.nlm.nih.gov/pubmed/23962922
http://dx.doi.org/10.1038/tp.2013.62

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