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Retrotransposon-Encoded Reverse Transcriptase in the Genesis, Progression and Cellular Plasticity of Human Cancer

LINE-1 (Long Interspersed Nuclear Elements) and HERVs (Human Endogenous Retroviruses) are two families of autonomously replicating retrotransposons that together account for about 28% of the human genome. Genes harbored within LINE-1 and HERV retrotransposons, particularly those encoding the reverse...

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Detalles Bibliográficos
Autores principales: Sinibaldi-Vallebona, Paola, Matteucci, Claudia, Spadafora, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756407/
https://www.ncbi.nlm.nih.gov/pubmed/24212657
http://dx.doi.org/10.3390/cancers3011141