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Long-term safety of pegloticase in chronic gout refractory to conventional treatment

OBJECTIVE: To evaluate the long-term safety (up to 3 years) of treatment with pegloticase in patients with refractory chronic gout. METHODS: This open-label extension (OLE) study was conducted at 46 sites in the USA, Canada and Mexico. Patients completing either of two replicate randomised placebo-c...

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Detalles Bibliográficos
Autores principales: Becker, Michael A, Baraf, Herbert S B, Yood, Robert A, Dillon, Aileen, Vázquez-Mellado, Janitzia, Ottery, Faith D, Khanna, Dinesh, Sundy, John S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756467/
https://www.ncbi.nlm.nih.gov/pubmed/23144450
http://dx.doi.org/10.1136/annrheumdis-2012-201795