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Differences in Specificity and Selectivity Between CBP and p300 Acetylation of Histone H3 and H3/H4

[Image: see text] Although p300 and CBP lysine acetyltransferases are often treated interchangeably, the inability of one enzyme to compensate for the loss of the other suggests unique roles for each. As these deficiencies coincide with aberrant levels of histone acetylation, we hypothesized that th...

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Detalles Bibliográficos
Autores principales: Henry, Ryan A., Kuo, Yin-Ming, Andrews, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756530/
https://www.ncbi.nlm.nih.gov/pubmed/23862699
http://dx.doi.org/10.1021/bi400684q