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WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion

Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) is an important regulator of vesicle trafficking. By generating actin on the surface of intracellular vesicles, WASH is able to directly regulate endosomal sorting and maturation. We report that, in Dictyostelium, WASH is also required for t...

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Detalles Bibliográficos
Autores principales: King, Jason S., Gueho, Aurélie, Hagedorn, Monica, Gopaldass, Navin, Leuba, Florence, Soldati, Thierry, Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756923/
https://www.ncbi.nlm.nih.gov/pubmed/23885127
http://dx.doi.org/10.1091/mbc.E13-02-0092