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WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion
Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) is an important regulator of vesicle trafficking. By generating actin on the surface of intracellular vesicles, WASH is able to directly regulate endosomal sorting and maturation. We report that, in Dictyostelium, WASH is also required for t...
Autores principales: | King, Jason S., Gueho, Aurélie, Hagedorn, Monica, Gopaldass, Navin, Leuba, Florence, Soldati, Thierry, Insall, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756923/ https://www.ncbi.nlm.nih.gov/pubmed/23885127 http://dx.doi.org/10.1091/mbc.E13-02-0092 |
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