Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability

How subunit dosage contributes to the assembly and function of multimeric complexes is an important question with implications in understanding biochemical, evolutionary, and disease mechanisms. Toward identifying pathways that are susceptible to decreased gene dosage, we performed a genome-wide scr...

Descripción completa

Detalles Bibliográficos
Autores principales: Choy, John S., O'Toole, Eileen, Schuster, Breanna M., Crisp, Matthew J., Karpova, Tatiana S., McNally, James G., Winey, Mark, Gardner, Melissa K., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756926/
https://www.ncbi.nlm.nih.gov/pubmed/23825022
http://dx.doi.org/10.1091/mbc.E12-12-0902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756926/
https://www.ncbi.nlm.nih.gov/pubmed/23825022
http://dx.doi.org/10.1091/mbc.E12-12-0902

Ejemplares similares