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The Flavonoid Apigenin Downregulates CDK1 by Directly Targeting Ribosomal Protein S9

Flavonoids have been reported to inhibit tumor growth by causing cell cycle arrest. However, little is known about the direct targets of flavonoids in tumor growth inhibition. In the present study, we developed a novel method using magnetic FG beads to purify flavonoid-binding proteins, and identifi...

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Detalles Bibliográficos
Autores principales: Iizumi, Yosuke, Oishi, Masakatsu, Taniguchi, Tomoyuki, Goi, Wakana, Sowa, Yoshihiro, Sakai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756953/
https://www.ncbi.nlm.nih.gov/pubmed/24009741
http://dx.doi.org/10.1371/journal.pone.0073219