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Spatial Memory and Long-Term Object Recognition Are Impaired by Circadian Arrhythmia and Restored by the GABA(A)Antagonist Pentylenetetrazole

Performance on many memory tests varies across the day and is severely impaired by disruptions in circadian timing. We developed a noninvasive method to permanently eliminate circadian rhythms in Siberian hamsters (Phodopussungorus) so that we could investigate the contribution of the circadian syst...

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Detalles Bibliográficos
Autores principales: Ruby, Norman F., Fernandez, Fabian, Garrett, Alex, Klima, Jessy, Zhang, Pei, Sapolsky, Robert, Heller, H. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756994/
https://www.ncbi.nlm.nih.gov/pubmed/24009680
http://dx.doi.org/10.1371/journal.pone.0072433