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PI3K p110δ Is Expressed by gp38(−)CD31(+) and gp38(+)CD31(+) Spleen Stromal Cells and Regulates Their CCL19, CCL21, and LTβR mRNA Levels

The role of p110δ PI3K in lymphoid cells has been studied extensively, showing its importance in immune cell differentiation, activation and development. Altered T cell localization in p110δ-deficient mouse spleen suggested a role for p110δ in non-hematopoietic stromal cells, which maintain hematopo...

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Detalles Bibliográficos
Autores principales: Zotes, Teresa M., Spada, Roberto, Mulens, Vladimir, Pérez-Yagüe, Sonia, Sorzano, Carlos O., Okkenhaug, Klaus, Carrera, Ana C., Barber, Domingo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757018/
https://www.ncbi.nlm.nih.gov/pubmed/24009720
http://dx.doi.org/10.1371/journal.pone.0072960