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Immunization against a Saccharide Epitope Accelerates Clearance of Experimental Gonococcal Infection

The emergence of ceftriaxone-resistant strains of Neisseria gonorrhoeae may herald an era of untreatable gonorrhea. Vaccines against this infection are urgently needed. The 2C7 epitope is a conserved oligosaccharide (OS) structure, a part of lipooligosaccharide (LOS) on N gonorrhoeae. The epitope is...

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Detalles Bibliográficos
Autores principales: Gulati, Sunita, Zheng, Bo, Reed, George W., Su, Xiaohong, Cox, Andrew D., St. Michael, Frank, Stupak, Jacek, Lewis, Lisa A., Ram, Sanjay, Rice, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757034/
https://www.ncbi.nlm.nih.gov/pubmed/24009500
http://dx.doi.org/10.1371/journal.ppat.1003559