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A Critical Function of Mad2l2 in Primordial Germ Cell Development of Mice

The development of primordial germ cells (PGCs) involves several waves of epigenetic reprogramming. A major step is following specification and involves the transition from the stably suppressive histone modification H3K9me2 to the more flexible, still repressive H3K27me3, while PGCs are arrested in...

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Detalles Bibliográficos
Autores principales: Pirouz, Mehdi, Pilarski, Sven, Kessel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757036/
https://www.ncbi.nlm.nih.gov/pubmed/24009519
http://dx.doi.org/10.1371/journal.pgen.1003712