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Functional Specialization of the Small Interfering RNA Pathway in Response to Virus Infection

In Drosophila, post-transcriptional gene silencing occurs when exogenous or endogenous double stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer-2 (Dcr-2) in association with a dsRNA-binding protein (dsRBP) cofactor called Loquacious (Loqs-PD). siRNAs are then loaded ont...

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Detalles Bibliográficos
Autores principales: Marques, Joao Trindade, Wang, Ji-Ping, Wang, Xiaohong, de Oliveira, Karla Pollyanna Vieira, Gao, Catherine, Aguiar, Eric Roberto Guimaraes Rocha, Jafari, Nadereh, Carthew, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757037/
https://www.ncbi.nlm.nih.gov/pubmed/24009507
http://dx.doi.org/10.1371/journal.ppat.1003579