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Functional Specialization of the Small Interfering RNA Pathway in Response to Virus Infection
In Drosophila, post-transcriptional gene silencing occurs when exogenous or endogenous double stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer-2 (Dcr-2) in association with a dsRNA-binding protein (dsRBP) cofactor called Loquacious (Loqs-PD). siRNAs are then loaded ont...
Autores principales: | Marques, Joao Trindade, Wang, Ji-Ping, Wang, Xiaohong, de Oliveira, Karla Pollyanna Vieira, Gao, Catherine, Aguiar, Eric Roberto Guimaraes Rocha, Jafari, Nadereh, Carthew, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757037/ https://www.ncbi.nlm.nih.gov/pubmed/24009507 http://dx.doi.org/10.1371/journal.ppat.1003579 |
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