Conditional Cooperativity of Toxin - Antitoxin Regulation Can Mediate Bistability between Growth and Dormancy

Many toxin-antitoxin operons are regulated by the toxin/antitoxin ratio by mechanisms collectively coined “conditional cooperativity”. Toxin and antitoxin form heteromers with different stoichiometric ratios, and the complex with the intermediate ratio works best as a transcription repressor. This a...

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Detalles Bibliográficos
Autores principales: Cataudella, Ilaria, Sneppen, Kim, Gerdes, Kenn, Mitarai, Namiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757081/
https://www.ncbi.nlm.nih.gov/pubmed/24009488
http://dx.doi.org/10.1371/journal.pcbi.1003174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757081/
https://www.ncbi.nlm.nih.gov/pubmed/24009488
http://dx.doi.org/10.1371/journal.pcbi.1003174

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