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Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery

The identification of cancer drivers is a major goal of current cancer research. Finding driver genes within large chromosomal events is especially challenging because such alterations encompass many genes. Previously, we demonstrated that zebrafish malignant peripheral nerve sheath tumors (MPNSTs)...

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Detalles Bibliográficos
Autores principales: Zhang, GuangJun, Hoersch, Sebastian, Amsterdam, Adam, Whittaker, Charles A., Beert, Eline, Catchen, Julian M., Farrington, Sarah, Postlethwait, John H., Legius, Eric, Hopkins, Nancy, Lees, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757083/
https://www.ncbi.nlm.nih.gov/pubmed/24009526
http://dx.doi.org/10.1371/journal.pgen.1003734