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Polydnaviral Ankyrin Proteins Aid Parasitic Wasp Survival by Coordinate and Selective Inhibition of Hematopoietic and Immune NF-kappa B Signaling in Insect Hosts

Polydnaviruses are mutualists of their parasitoid wasps and express genes in immune cells of their Lepidopteran hosts. Polydnaviral genomes carry multiple copies of viral ankyrins or vankyrins. Vankyrin proteins are homologous to IκB proteins, but lack sequences for regulated degradation. We tested...

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Detalles Bibliográficos
Autores principales: Gueguen, Gwenaelle, Kalamarz, Marta E., Ramroop, Johnny, Uribe, Jeffrey, Govind, Shubha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757122/
https://www.ncbi.nlm.nih.gov/pubmed/24009508
http://dx.doi.org/10.1371/journal.ppat.1003580