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Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones

Syntheses and biological activities of imidazo-, pyrimido- and diazepino[2,1-f]purinediones containing N-alkyl substituents (with straight, branched or unsaturated chains) are described. Tricyclic derivatives were synthesized by the cyclization of 8-bromo-substituted 7-(2-bromoethyl)-, 7-(3-chloropr...

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Detalles Bibliográficos
Autores principales: Drabczyńska, Anna, Karcz, Tadeusz, Szymańska, Ewa, Köse, Meryem, Müller, Christa E., Paskaleva, Minka, Karolak-Wojciechowska, Janina, Handzlik, Jadwiga, Yuzlenko, Olga, Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757144/
https://www.ncbi.nlm.nih.gov/pubmed/23543220
http://dx.doi.org/10.1007/s11302-013-9358-3