pRb controls Estrogen Receptor alpha protein stability and activity

A cross talk between the Estrogen Receptor (ESR1) and the Retinoblastoma (pRb) pathway has been demonstrated to influence the therapeutic response of breast cancer patients but the full mechanism remains poorly understood. Here we show that the N-terminal domain of pRb interacts with the CD domain o...

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Detalles Bibliográficos
Autores principales: Caligiuri, Isabella, Toffoli, Giuseppe, Giordano, Antonio, Rizzolio, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757244/
https://www.ncbi.nlm.nih.gov/pubmed/23900261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757244/
https://www.ncbi.nlm.nih.gov/pubmed/23900261

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