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Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer

Breast cancer is a leading form of cancer in the world. The Drosophila Dac gene was cloned as an inhibitor of the hyperactive epidermal growth factor (EGFR), ellipse. Herein, endogenous DACH1 co-localized with p53 in a nuclear, extranucleolar compartment and bound to p53 in human breast cancer cell...

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Detalles Bibliográficos
Autores principales: Chen, Ke, Wu, Kongming, Gormley, Michael, Ertel, Adam, Wang, Jing, Zhang, Wei, Zhou, Jie, DiSante, Gabriele, Li, Zhiping, Rui, Hallgeir, Quong, Andrew A., McMahon, Steven B., Deng, Haiteng, Lisanti, Michael P., Wang, Chenguang, Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757249/
https://www.ncbi.nlm.nih.gov/pubmed/23798621