Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5

The c-Myc (Myc) oncoprotein is a high-value therapeutic target given that it is deregulated in multiple types of cancer. However, potent small molecule inhibitors of Myc have been difficult to identify, particularly those whose mechanism relies on blocking the association between Myc and its obligat...

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Detalles Bibliográficos
Autores principales: Wang, Huabo, Chauhan, Jay, Hu, Angela, Pendleton, Kelsey, Yap, Jeremy L., Sabato, Philip E., Jones, Jace W., Perri, Mariarita, Yu, Jianshi, Cione, Erika, Kane, Maureen A., Fletcher, Steven, Prochownik, Edward V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757250/
https://www.ncbi.nlm.nih.gov/pubmed/23801058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757250/
https://www.ncbi.nlm.nih.gov/pubmed/23801058

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