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Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?

The common preference of cancers for lactic acid-generating metabolic energy pathways has led to proposals that their reprogrammed metabolism confers growth advantages such as decreased susceptibility to hypoxic stress. Recent observations, however, suggest that it generates a novel way for cancer s...

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Detalles Bibliográficos
Autores principales: Choi, Stephen Yiu Chuen, Collins, Colin C, Gout, Peter W, Wang, Yuzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757307/
https://www.ncbi.nlm.nih.gov/pubmed/23729358
http://dx.doi.org/10.1002/path.4218