Kinetic Evidence of an Apparent Negative Activation Enthalpy in an Organocatalytic Process

A combined kinetic and computational study on our tryptophan-based bifunctional thiourea catalyzed asymmetric Mannich reactions reveals an apparent negative activation enthalpy. The formation of the pre-transition state complex has been unambiguously confirmed and these observations provide an exper...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiao, Lee, Richmond, Chen, Tao, Luo, Jie, Lu, Yixin, Huang, Kuo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757351/
https://www.ncbi.nlm.nih.gov/pubmed/23990028
http://dx.doi.org/10.1038/srep02557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757351/
https://www.ncbi.nlm.nih.gov/pubmed/23990028
http://dx.doi.org/10.1038/srep02557

Ejemplares similares