Cargando…
Kinetic Evidence of an Apparent Negative Activation Enthalpy in an Organocatalytic Process
A combined kinetic and computational study on our tryptophan-based bifunctional thiourea catalyzed asymmetric Mannich reactions reveals an apparent negative activation enthalpy. The formation of the pre-transition state complex has been unambiguously confirmed and these observations provide an exper...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757351/ https://www.ncbi.nlm.nih.gov/pubmed/23990028 http://dx.doi.org/10.1038/srep02557 |