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Wnt/β-catenin Signaling in Normal and Cancer Stem Cells

The ability of Wnt ligands to initiate a signaling cascade that results in cytoplasmic stabilization of, and nuclear localization of, β-catenin underlies their ability to regulate progenitor cell differentiation. In this review, we will summarize the current knowledge of the mechanisms underlying Wn...

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Detalles Bibliográficos
Autores principales: Valkenburg, Kenneth C., Graveel, Carrie R., Zylstra-Diegel, Cassandra R., Zhong, Zhendong, Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757404/
https://www.ncbi.nlm.nih.gov/pubmed/24212796
http://dx.doi.org/10.3390/cancers3022050