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Lipofuscin: formation, effects and role of macroautophagy()

Oxidative stress plays a crucial role in the development of the aging process and age dependent diseases. Both are closely connected to disturbances of proteostasis by protein oxidation and an impairment of the proteasomal system. The final consequence is the accumulation of highly cross-linked unde...

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Detalles Bibliográficos
Autores principales: Höhn, Annika, Grune, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757681/
https://www.ncbi.nlm.nih.gov/pubmed/24024146
http://dx.doi.org/10.1016/j.redox.2013.01.006