Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging()

The elimination of oxidatively modified proteins is a crucial process in maintaining cellular homeostasis, especially during stress. Mitochondria are protein-dense, high traffic compartments, whose polypeptides are constantly exposed to superoxide, hydrogen peroxide, and other reactive species, gene...

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Detalles Bibliográficos
Autores principales: Ngo, Jenny K., Pomatto, Laura C.D., Davies, Kelvin J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757690/
https://www.ncbi.nlm.nih.gov/pubmed/24024159
http://dx.doi.org/10.1016/j.redox.2013.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757690/
https://www.ncbi.nlm.nih.gov/pubmed/24024159
http://dx.doi.org/10.1016/j.redox.2013.01.015

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