Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1()()

Cigarette smoking remains a major health concern worldwide, and many of the adverse effects of cigarette smoke (CS) can be attributed to its abundant electrophilic aldehydes, such as acrolein (2-propenal). Previous studies indicate that acrolein readily reacts with thioredoxin reductase 1 (TrxR1), a...

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Detalles Bibliográficos
Autores principales: Randall, Matthew J., Spiess, Page C., Hristova, Milena, Hondal, Robert J., van der Vliet, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757691/
https://www.ncbi.nlm.nih.gov/pubmed/24024160
http://dx.doi.org/10.1016/j.redox.2013.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757691/
https://www.ncbi.nlm.nih.gov/pubmed/24024160
http://dx.doi.org/10.1016/j.redox.2013.02.001

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