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Extracellular but not cytosolic superoxide dismutase protects against oxidant-mediated endothelial dysfunction()

Superoxide (O(2)(•−)) contributes to the development of cardiovascular disease. Generation of O(2)(•−) occurs in both the intracellular and extracellular compartments. We hypothesized that the gene transfer of cytosolic superoxide dismutase (SOD1) or extracellular SOD (SOD3) to blood vessels would d...

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Detalles Bibliográficos
Autores principales: Foresman, Erin L., Miller, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757697/
https://www.ncbi.nlm.nih.gov/pubmed/24024163
http://dx.doi.org/10.1016/j.redox.2013.04.003