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Extracellular but not cytosolic superoxide dismutase protects against oxidant-mediated endothelial dysfunction()
Superoxide (O(2)(•−)) contributes to the development of cardiovascular disease. Generation of O(2)(•−) occurs in both the intracellular and extracellular compartments. We hypothesized that the gene transfer of cytosolic superoxide dismutase (SOD1) or extracellular SOD (SOD3) to blood vessels would d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757697/ https://www.ncbi.nlm.nih.gov/pubmed/24024163 http://dx.doi.org/10.1016/j.redox.2013.04.003 |