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Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3

Mesenchymal stromal cells (MSCs) are multilineage progenitors with immunomodulatory properties, including expansion of immunomodulatory leukocytes such as regulatory T lymphocytes (Tregs) and tolerogenic dendritic cells. We report that human MSCs can expand CD14(−)CD11b(+)CD33(+) human myeloid-deriv...

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Detalles Bibliográficos
Autores principales: Yen, B. Linju, Yen, Men-Luh, Hsu, Pei-Ju, Liu, Ko-Jiunn, Wang, Chia-Jen, Bai, Chyi-Huey, Sytwu, Huey-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757753/
https://www.ncbi.nlm.nih.gov/pubmed/24052949
http://dx.doi.org/10.1016/j.stemcr.2013.06.006