Self micro-emulsifying drug delivery system of tacrolimus: Formulation, in vitro evaluation and stability studies

BACKGROUND: Tacrolimus has poor solubility in water ranging from 4 to 12 μg/mL. The oral bio availabilities of tacrolimus is poor and exhibits high intra and inter-subject variability (4-89%, average 25%) in the liver and the kidney transplant recipients and in patients with renal impairment. AIM: T...

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Detalles Bibliográficos
Autores principales: Patel, Pranav V, Patel, Hitesh K, Panchal, Shital S, Mehta, Tejal A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757905/
https://www.ncbi.nlm.nih.gov/pubmed/24015381
http://dx.doi.org/10.4103/2230-973X.114899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757905/
https://www.ncbi.nlm.nih.gov/pubmed/24015381
http://dx.doi.org/10.4103/2230-973X.114899

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