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Self micro-emulsifying drug delivery system of tacrolimus: Formulation, in vitro evaluation and stability studies
BACKGROUND: Tacrolimus has poor solubility in water ranging from 4 to 12 μg/mL. The oral bio availabilities of tacrolimus is poor and exhibits high intra and inter-subject variability (4-89%, average 25%) in the liver and the kidney transplant recipients and in patients with renal impairment. AIM: T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757905/ https://www.ncbi.nlm.nih.gov/pubmed/24015381 http://dx.doi.org/10.4103/2230-973X.114899 |