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Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells

A number of exendin derivatives have been developed to target glucagon-like peptide 1 (GLP-1) receptors on beta cells in vivo. Modifications of exendin analogues have been shown to have significant effects on pharmacokinetics and, as such, have been used to develop a variety of therapeutic compounds...

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Detalles Bibliográficos
Autores principales: Keliher, Edmund J, Reiner, Thomas, Thurber, Greg M, Upadhyay, Rabi, Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758109/
https://www.ncbi.nlm.nih.gov/pubmed/23997998
http://dx.doi.org/10.1002/open.201200014