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Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells
A number of exendin derivatives have been developed to target glucagon-like peptide 1 (GLP-1) receptors on beta cells in vivo. Modifications of exendin analogues have been shown to have significant effects on pharmacokinetics and, as such, have been used to develop a variety of therapeutic compounds...
Autores principales: | Keliher, Edmund J, Reiner, Thomas, Thurber, Greg M, Upadhyay, Rabi, Weissleder, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758109/ https://www.ncbi.nlm.nih.gov/pubmed/23997998 http://dx.doi.org/10.1002/open.201200014 |
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