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Notch Signaling Limits Supporting Cell Plasticity in the Hair Cell-Damaged Early Postnatal Murine Cochlea

In mammals, auditory hair cells are generated only during embryonic development and loss or damage to hair cells is permanent. However, in non-mammalian vertebrate species, such as birds, neighboring glia-like supporting cells regenerate auditory hair cells by both mitotic and non-mitotic mechanisms...

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Detalles Bibliográficos
Autores principales: Korrapati, Soumya, Roux, Isabelle, Glowatzki, Elisabeth, Doetzlhofer, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758270/
https://www.ncbi.nlm.nih.gov/pubmed/24023676
http://dx.doi.org/10.1371/journal.pone.0073276