Cargando…
Notch Signaling Limits Supporting Cell Plasticity in the Hair Cell-Damaged Early Postnatal Murine Cochlea
In mammals, auditory hair cells are generated only during embryonic development and loss or damage to hair cells is permanent. However, in non-mammalian vertebrate species, such as birds, neighboring glia-like supporting cells regenerate auditory hair cells by both mitotic and non-mitotic mechanisms...
Autores principales: | Korrapati, Soumya, Roux, Isabelle, Glowatzki, Elisabeth, Doetzlhofer, Angelika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758270/ https://www.ncbi.nlm.nih.gov/pubmed/24023676 http://dx.doi.org/10.1371/journal.pone.0073276 |
Ejemplares similares
-
Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
por: Li, Xiao-Jun, et al.
Publicado: (2022) -
A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
por: Prajapati-DiNubila, Meenakshi, et al.
Publicado: (2019) -
Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea
por: Ni, Wenli, et al.
Publicado: (2016) -
Lgr5-Positive Supporting Cells Generate New Hair Cells in the Postnatal Cochlea
por: Bramhall, Naomi F., et al.
Publicado: (2014) -
Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea
por: Zhang, Shasha, et al.
Publicado: (2019)