The Dopamine D3 Receptor Knockout Mouse Mimics Aging-Related Changes in Autonomic Function and Cardiac Fibrosis

Blood pressure increases with age, and dysfunction of the dopamine D3 receptor has been implicated in the pathogenesis of hypertension. To evaluate the role of the D3 receptor in aging-related hypertension, we assessed cardiac structure and function in differently aged (2 mo, 1 yr, 2 yr) wild type (...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Tracy L., Tulis, David A., Keeler, Benjamin E., Virag, Jitka A., Lust, Robert M., Clemens, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758275/
https://www.ncbi.nlm.nih.gov/pubmed/24023697
http://dx.doi.org/10.1371/journal.pone.0074116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758275/
https://www.ncbi.nlm.nih.gov/pubmed/24023697
http://dx.doi.org/10.1371/journal.pone.0074116

Ejemplares similares