Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective loss of motor neurons in the spinal cord, brain stem, and motor cortex. Mutations in superoxide dismutase (SOD1) are associated with familial ALS and lead to SOD1 protein misfolding and aggregati...

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Detalles Bibliográficos
Autores principales: Novoselov, Sergey S., Mustill, Wendy J., Gray, Anna L., Dick, James R., Kanuga, Naheed, Kalmar, Bernadett, Greensmith, Linda, Cheetham, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758296/
https://www.ncbi.nlm.nih.gov/pubmed/24023695
http://dx.doi.org/10.1371/journal.pone.0073944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758296/
https://www.ncbi.nlm.nih.gov/pubmed/24023695
http://dx.doi.org/10.1371/journal.pone.0073944

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