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A Novel CXCL10-Based GPI-Anchored Fusion Protein as Adjuvant in NK-Based Tumor Therapy

BACKGROUND: Cellular therapy is a promising therapeutic strategy for malignant diseases. The efficacy of this therapy can be limited by poor infiltration of the tumor by immune effector cells. In particular, NK cell infiltration is often reduced relative to T cells. A novel class of fusion proteins...

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Detalles Bibliográficos
Autores principales: Muenchmeier, Niklas, Boecker, Sophia, Bankel, Lorenz, Hinz, Laura, Rieth, Nicole, Lapa, Constantin, Mendler, Anna N., Noessner, Elfriede, Mocikat, Ralph, Nelson, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758322/
https://www.ncbi.nlm.nih.gov/pubmed/24023642
http://dx.doi.org/10.1371/journal.pone.0072749