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A Novel CXCL10-Based GPI-Anchored Fusion Protein as Adjuvant in NK-Based Tumor Therapy
BACKGROUND: Cellular therapy is a promising therapeutic strategy for malignant diseases. The efficacy of this therapy can be limited by poor infiltration of the tumor by immune effector cells. In particular, NK cell infiltration is often reduced relative to T cells. A novel class of fusion proteins...
Autores principales: | Muenchmeier, Niklas, Boecker, Sophia, Bankel, Lorenz, Hinz, Laura, Rieth, Nicole, Lapa, Constantin, Mendler, Anna N., Noessner, Elfriede, Mocikat, Ralph, Nelson, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758322/ https://www.ncbi.nlm.nih.gov/pubmed/24023642 http://dx.doi.org/10.1371/journal.pone.0072749 |
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