Engineered Mitochondrial Ferritin as a Magnetic Resonance Imaging Reporter in Mouse Olfactory Epithelium

We report the design of a MRI reporter gene with applications to non-invasive molecular imaging. We modified mitochondrial ferritin to localize to the cell cytoplasm. We confirmed the efficient cellular processing of this engineered protein and demonstrated high iron loading in mammalian cells. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Iordanova, Bistra, Hitchens, T. Kevin, Robison, Clinton S., Ahrens, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758330/
https://www.ncbi.nlm.nih.gov/pubmed/24023635
http://dx.doi.org/10.1371/journal.pone.0072720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758330/
https://www.ncbi.nlm.nih.gov/pubmed/24023635
http://dx.doi.org/10.1371/journal.pone.0072720

Ejemplares similares