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Caveolae Regulation of Mechanosensitive Channel Function in Myotubes

Mutations that lead to muscular dystrophy often create deficiencies in cytoskeletal support of the muscle sarcolemma causing hyperactive mechanosensitive cation channel (MSC) activity and elevated intracellular Ca(2+). Caveolae are cholesterol-rich microdomains that form mechanically deformable inva...

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Detalles Bibliográficos
Autores principales: Huang, Haixia, Bae, Chilman, Sachs, Frederick, Suchyna, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758351/
https://www.ncbi.nlm.nih.gov/pubmed/24023653
http://dx.doi.org/10.1371/journal.pone.0072894